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It fights bacteria in your body. <li>Cotrimoxazole is used to treat infections such as urinary tract infections, bronchitis, ear infections (otitis), traveler's diarrhea, and Pneumocystis carinii pneumonia. <li>Cotrimoxazole may also be used for purposes other than those listed in this medication guide. </ul> <b>What should I discuss with my doctor before taking Cotrimoxazole? </b><ul> <li>Before taking this medication, tell your doctor if you have<ul> <li>kidney or liver disease, or <li>a glucose-6-phosphate dehydrogenase deficiency (G6PD deficiency). </ul> <li>You may not be able to take Cotrimoxazole, or you may require a lower dose or special monitoring during treatment if you have any of the conditions listed above. <li>Cotrimoxazole is in the FDA pregnancy category C. This means that it is not known whether sulfamethoxazole and trimethoprim will harm an unborn baby. 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